Biolog Phenotype MicroArray
     Serious Technology for Serious Microbiology
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Useful Links

Regulation of Toxix Production and Secondary Metabolic Pathways Studied with PM Technology

Phenotype MicroArray
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  Nutrient profiling reveals potent inducers of trichothecene biosynthesis in Fusarium graminearum
Donald M. Gardiner *, Kemal Kazan, John M. Manners CSIRO Plant Industry, Queensland Bioscience Precinct, 306 Carmody Road, St. Lucia, Queensland 4067, Australia Fungal Genet Biol. 2009 Aug;46(8):604-13. Epub 2009 May 3. Donald Gardiner's group used Phenotype MicroArrays and a GFP reporter gene to identify inducers of tricothecene biosynthesis. A copy of the paper can be downloaded at this link.
 
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 Application of Biolog FF MicroPlate for substrate utilization and metabolite profiling of closely related fungi
Singh MP. Chemical and Screening Sciences, Wyeth Research, Pearl River, NY 10965, United States. singhm@wyeth.com J Microbiol Methods. 2009 Apr;77(1):102-8. Epub 2009 Feb 5. In this breakthrough paper, Biolog plates were used to determine culture conditions for a fungus to maximize production of antibacterial and other important chemicals produced by secondary metabolic pathways. A copy of the paper can be downloaded at this link.
 
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Phenotype MicroArray Technology
Biolog's Phentoype MicroArray technology enables researchers to evaluate nearly 2000 phenotypes of a microbial cell in a single experiment. This integrated system of cellular assays, instrumentation and bioinformatics software provides cellular knowledge that complements molecular information, helping you interpret and find the relevant aspects in massive amounts of gene expression or proteomics data. Through comprehensive and precise quantitation of phenotypes, researchers are able to obtain an unbiased perspective of the effect on cells of genetic differences, environmental change, exposure to chemicals or drugs, and more.
 
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