Biolog Phenotype MicroArray
     Serious Technology for Serious Microbiology October 2006
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Useful Links

New Publications using Phenotype MicroArray Technology

Phenotype MicroArray
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  Identification of SNPs in two Salmonella enterica serovar Enteritidis PT13a pathotypes that point to epidemiological trends
There has been an increasing number of infections leading to salmonellosis by Salmonella enterica serovar Enteritidis in the United States. Using preliminary genomic sequence data of Salmonella enterica subsp. I serovar Enteritidis PT4 from the Sanger Institute as a starting point, researchers at The Egg Safety and Quality Research Unit (ESQRU) of the U. S. Department of Agriculture have identified a set of potential SNPs that point to differences between two PT13a pathotypes that may be relevant in distinguishing phenotypic traits that may have epidemiological consequences.
 
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  Exploring Genotypic and Phenotypic Diversity of Microbes Using Microarray Approaches
This overview article from the FDA research lab discusses the usefulness of data obtained from doing Phenotype MicroArray analyses of collections of pathogenic species from outbreaks of food poisoning. Data from PM analyses is combined with other modern approaches such as DNA tiling microarrays to relate genetic changes (SNPs) with cellular characteristics important in pathogenicity and epidemiology.
 
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Phenotype MicroArray Technology
Biolog's Phentoype MicroArray technology enables researchers to evaluate nearly 2000 phenotypes of a microbial cell in a single experiment. This integrated system of cellular assays, instrumentation and bioinformatics software provides cellular knowledge that complements molecular information, helping you interpret and find the relevant aspects in massive amounts of gene expression or proteomics data. Through comprehensive and precise quantitation of phenotypes, researchers are able to obtain an unbiased perspective of the effect on cells of genetic differences, environmental change, exposure to chemicals or drugs, and more.
 
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